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KMID : 1144320160480010031
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감염과 화학요법
2016 Volume.48 No. 1 p.31 ~ p.35
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Fecal Transplantation using a Nasoenteric Tube during an Initial Episode of Severe Clostridium difficile Infection
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:Jeon Yong-Duk
:Hong Nam-Ki/:Kim Jung-Ho/:Park Se-Hee/:Kim Sung-Bae/:Song In-Ji/:Ann Hea-Won/:Ahn Jin-Young/:Kim Sun-Bean/:Ku Nam-Su/:Lee Kyung-Won/:Yong Dong-Eun/:Kim June-Myung/:Choi Jun-Yong
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Abstract
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The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
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KEYWORD
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Fecal transplantation, Fecal microbiota, Clostridium difficile, Nasoenteric tube
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